Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3618933 | 0.84 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL6177938 | 0.83 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL6173806 | 0.82 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL6176174 | 0.82 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL6177219 | 0.82 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL6175342 | 0.81 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL6176543 | 0.80 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL6176968 | 0.79 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL8006677 | 0.79 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 | |
| SCHEMBL10757128 | 0.79 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KDM4EPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880531-A1 | SUBSTITUTED 2-PHENYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997030059-A1 | SUBSTITUTED 2-PHENYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1997-08-21 | — | — | WO | disclosed |