Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | MPC2 | O95563 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24599231 | 0.80 | PPARG (0.72) | PPARGCYP3A4RXRACYP2C9MPC2 | |
| SCHEMBL8660907 | 0.80 | PPARG (0.53) | PPARGKDM4EMAPTCYP3A4RXRA | |
| SCHEMBL19217761 | 0.79 | PPARG (0.68) | PPARGCYP3A4RXRACYP2C9MPC2 | |
| SCHEMBL6032172 | 0.75 | MAPT (0.53) | PPARGKDM4EMAPTCYP3A4CYP2C9 | |
| SCHEMBL6928369 | 0.71 | PPARG (1.00) | PPARGMAPTCYP3A4RXRACYP2C9 | |
| SCHEMBL6929811 | 0.71 | PPARG (1.00) | PPARGMAPTCYP3A4RXRACYP2C9 | |
| SCHEMBL2328760 | 0.71 | PPARG (1.00) | PPARGMAPTCYP3A4RXRACYP2C9 | |
| SCHEMBL2328758 | 0.71 | PPARG (1.00) | PPARGMAPTCYP3A4RXRACYP2C9 | |
| SCHEMBL23836844 | 0.71 | PPARG (1.00) | PPARGMAPTCYP3A4RXRACYP2C9 | |
| SCHEMBL18541508 | 0.71 | PPARG (1.00) | PPARGMAPTCYP3A4RXRACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824694-A | Thiazolidine derivatives for the treatment of psoriasis | BETHESDA PHARMACEUTICALS, INC. (US) | 1998-10-20 | — | — | US | disclosed |