Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469293 | 0.85 | MAPT (0.56) | MAPTKDM4EPPARGMAOBCYP1A2 | |
| SCHEMBL8486948 | 0.79 | MAPT (0.44) | MAPTKDM4EPPARGMAOBCYP1A2 | |
| SCHEMBL8523887 | 0.77 | MAPT (0.43) | MAPTKDM4EPPARGMAOBCYP1A2 | |
| SCHEMBL8660907 | 0.77 | PPARG (0.53) | MAPTKDM4EPPARGCYP1A2CYP3A4 | |
| SCHEMBL8472101 | 0.77 | MAPT (0.41) | MAPTKDM4EPPARGMAOBCYP1A2 | |
| SCHEMBL8687360 | 0.77 | PPARG (0.48) | MAPTKDM4EPPARGCYP1A2CYP3A4 | |
| SCHEMBL8524315 | 0.77 | FFAR1 (0.53) | MAPTKDM4EPPARGCYP1A2CYP3A4 | |
| SCHEMBL8664520 | 0.75 | PPARG (0.56) | MAPTKDM4EPPARGCYP1A2CYP3A4 | |
| SCHEMBL8484201 | 0.75 | SIGMAR1 (0.45) | MAPTKDM4E | |
| SCHEMBL8659791 | 0.75 | MAPT (0.44) | MAPTKDM4EPPARGCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052627-A1 | Novel modulators of the PPAR-type receptors and cosmetic/pharmaceutical compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-03-09 | — | — | US | disclosed |
| EP-0555249-A1 | THIAZOLIDINEDIONE DERIVATIVES | BEECHAM GROUP plc (GB) | 1993-08-18 | — | — | EP | disclosed |
| US-4725610-A | TREATMENT OF HYPERLIPEMIA AND DIABETES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052627-A1 | Novel modulators of the PPAR-type receptors and cosmetic/pharmaceutical compositions comprised thereof | PPARG, PPARD, PPARA | MAPT 3674/4885KDM4E 3115/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.