Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664523 | 0.85 | MAPT (0.36) | NR3C1PGRARTSHRALDH1A1 | |
| SCHEMBL8641578 | 0.81 | TSHR (0.47) | TSHRALDH1A1MAPTKCNJ1LMNA | |
| SCHEMBL7756479 | 0.78 | TSHR (0.45) | TSHRALDH1A1MAPTKCNJ1LMNA | |
| SCHEMBL7753019 | 0.78 | TSHR (0.45) | TSHRALDH1A1MAPTKCNJ1LMNA | |
| SCHEMBL7756447 | 0.76 | TSHR (0.41) | NR3C1PGRARTSHRALDH1A1 | |
| SCHEMBL7753030 | 0.76 | TSHR (0.41) | NR3C1PGRARTSHRALDH1A1 | |
| SCHEMBL7757180 | 0.74 | TSHR (0.44) | NR3C1PGRARTSHRALDH1A1 | |
| SCHEMBL7756415 | 0.71 | MAPT (0.42) | NR3C1PGRARTSHRALDH1A1 | |
| SCHEMBL7755756 | 0.70 | TSHR (0.42) | TSHRALDH1A1MAPTKCNJ1LMNA | |
| SCHEMBL7753025 | 0.69 | LOXL2 (0.39) | TSHRALDH1A1MAPTKCNJ1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741784-A | ADMINISTERING TO TREAT METABOLIC BONE DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-21 | — | — | US | disclosed |