Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TLR3 | O15455 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664526 | 0.85 | NR3C1 (0.39) | MAPTALDH1A1KCNJ1LMNASMN1; SMN2 | |
| SCHEMBL8641571 | 0.79 | LOXL2 (0.47) | MAPTALDH1A1KCNJ1LMNASMN1; SMN2 | |
| SCHEMBL7756470 | 0.77 | LOXL2 (0.44) | MAPTALDH1A1KCNJ1LMNASMN1; SMN2 | |
| SCHEMBL2031931 | 0.77 | LOXL2 (0.44) | MAPTALDH1A1KCNJ1LMNASMN1; SMN2 | |
| SCHEMBL7756435 | 0.76 | LOXL2 (0.39) | MAPTALDH1A1KCNJ1LMNASMN1; SMN2 | |
| SCHEMBL7753025 | 0.76 | LOXL2 (0.39) | MAPTALDH1A1KCNJ1LMNASMN1; SMN2 | |
| SCHEMBL7757176 | 0.74 | LOXL2 (0.42) | MAPTALDH1A1KCNJ1LMNASMN1; SMN2 | |
| SCHEMBL7753030 | 0.71 | TSHR (0.41) | MAPTALDH1A1KCNJ1LMNASMN1; SMN2 | |
| SCHEMBL7756447 | 0.71 | TSHR (0.41) | MAPTALDH1A1KCNJ1LMNASMN1; SMN2 | |
| SCHEMBL7756406 | 0.71 | MAPT (0.42) | MAPTALDH1A1KCNJ1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741784-A | ADMINISTERING TO TREAT METABOLIC BONE DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-21 | — | — | US | disclosed |