Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | SPOP | O43791 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664695 | 1.00 | PLCG1 (0.67) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL11682347 | 0.91 | PLCG1 (0.66) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL1010087 | 0.91 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL27938962 | 0.91 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL10820995 | 0.91 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL8533433 | 0.91 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL10840113 | 0.91 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| Methylene Chloride SCHEMBL11134298 | 0.91 | PLCG1 (0.65) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL11541672 | 0.91 | PLCG1 (0.82) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL7771463 | 0.91 | PLCG1 (0.67) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4208515-A | 3-Halo cephalosporins | ELI LILLY AND COMPANY (US) | 1980-06-17 | — | — | US | claimed |
| EP-0745603-B1 | Process for p-nitrobenzyl ester cleavage in cephalosporin | RANBAXY LAB LTD (IN) | 1998-12-02 | — | — | EP | disclosed |
| EP-0745603-A1 | Process for p-nitrobenzyl ester cleavage in cephalosporin | Ranbaxy Laboratories Limited (IN) | 1996-12-04 | — | — | EP | disclosed |
| US-5536830-A | Process for P-nitrobenzyl ester cleavage in cephalosporin | RANBAXY LABORATORIES, LTD. (IN) | 1996-07-16 | — | — | US | disclosed |
| EP-0096496-B1 | PREPARATION OF PENICILLIN AND CEPHALOSPORIN COMPOUNDS AND NOVEL INTERMEDIATES USEFUL THEREIN | Lilly Industries Limited (GB) | 1986-07-23 | — | — | EP | disclosed |
| EP-0014567-B1 | PROCESSES FOR PREPARATION OF BETA-LACTAM COMPOUNDS | ELI LILLY AND COMPANY (US) | 1984-01-18 | — | — | EP | disclosed |
| EP-0096496-A1 | Preparation of penicillin and cephalosporin compounds and novel intermediates useful therein | Lilly Industries Limited (GB) | 1983-12-21 | — | — | EP | disclosed |
| US-4281116-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4260745-A | 3-Halo cephalosporins | ELI LILLY AND COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4252950-A | ANTIBIOTICS, BACTERICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
| US-4211702-A | TRIARYLPHOSPHITE-HALOGEN COMPLEX HALOGENATING AGENT | ELI LILLY AND COMPANY (US) | 1980-07-08 | — | — | US | disclosed |
| US-4208515-A | 3-Halo cephalosporins | ELI LILLY AND COMPANY (US) | 1980-06-17 | — | — | US | disclosed |
| US-4115643-A | Process for 3-chloro cephalosporins | ELI LILLY AND COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4091214-A | ALPHA-HYDROXY CARBOXYLIC ACID | ELI LILLY AND COMPANY (US) | 1978-05-23 | — | — | US | disclosed |
| US-4065618-A | Process for 3-H-3-cephem esters | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4065621-A | Process for 3-alkyl and 3-phenyl cephalosporins | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4064343-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-4044002-A | ACYL BROMIDES AND A BROMINE SCAVENGER | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4013651-A | 3-SUBSTITUTED AMINO-CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-3962227-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |