Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KDM6B | O15054 | 1/20 | 0.54 |
| ▸ | KDM4A | O75164 | 1/20 | 0.54 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567878 | 0.88 | KDM4C (0.57) | ALDH1A1MAPTLMNAPKMMEN1 | |
| SCHEMBL3599482 | 0.86 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL4721194 | 0.82 | MEN1 (0.51) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL9540575 | 0.81 | MAPT (0.63) | ALDH1A1MAPTLMNAPKMHTT | |
| SCHEMBL102602 | 0.81 | MAPT (0.77) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL9368494 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL8252211 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAPKMMEN1 | |
| SCHEMBL9369879 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNAPKMMEN1 | |
| SCHEMBL28570276 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNAPKMMEN1 | |
| SCHEMBL2337025 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127231-A1 | PROCESS FOR THE PREPARTION OF AMIFAMPRIDINE PHOSPHATE | SHILPA MEDICARE LTD (IN) | 2022-04-28 | — | — | US | disclosed |
| US-10471139-B2 | Toll-like receptor agonists | THE UNIVERSITY OF KANSAS (US) | 2019-11-12 | — | — | US | disclosed |
| WO-2017168333-A1 | AMIFAMPRIDINE DIHYDROCHLORIDE | SHILPA MEDICARE LIMITED (IN) | 2017-10-05 | — | — | WO | disclosed |
| US-20160166681-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS | 2016-06-16 | — | — | US | disclosed |
| US-20160166681-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS | 2016-06-16 | — | — | US | disclosed |
| US-20160166681-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS | 2016-06-16 | — | — | US | disclosed |
| WO-2015023958-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS (US) | 2015-02-19 | — | — | WO | disclosed |
| WO-2015022332-A1 | PYRIDINONES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-19 | — | — | WO | disclosed |
| WO-2015023958-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS (US) | 2015-02-19 | — | — | WO | disclosed |
| US-5723468-A | COGNITION ACTIVATORS FOR MEMOY LOSS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-03-03 | — | — | US | disclosed |
| US-5571819-A | Imidazopyridines as muscarinic agents | WYETH | 1996-11-05 | — | — | US | disclosed |
| EP-0399653-B1 | Anticonvulsant triazolo[4,5-c]pyridine derivatives | WELLCOME FOUND (GB) | 1994-10-19 | — | — | EP | disclosed |
| US-5240937-A | Treatment of epilepsy | BURROUGHS WELLCOME CO. (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0399653-A1 | Anticonvulsant triazolo[4,5-c]pyridine derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |
| EP-0156495-A1 | Diaminopyridines via hydrogenation of nitrobenzylaminopyridines | ELI LILLY AND COMPANY (US) | 1985-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160166681-A1 | TOLL-LIKE RECEPTOR AGONISTS | TLR1, TLR7, TLR8 | ALDH1A1 1952/4885MAPT 323/4885LMNA 445/4885 |
| US-20220127231-A1 | PROCESS FOR THE PREPARTION OF AMIFAMPRIDINE PHOSPHATE | PMM2, TYMP, MVD | ALDH1A1 964/4885MAPT 3088/4885LMNA 1525/4885 |
| US-10471139-B2 | Toll-like receptor agonists | TLR1, TLR7, TLR8 | ALDH1A1 1952/4885MAPT 323/4885LMNA 445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.