Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | CASP1 | P29466 | 1/20 | 0.68 |
| ▸ | CASP7 | P55210 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 4/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664746 | 1.00 | MAPT (0.68) | MAPTALDH1A1TP53HPGDTDP1 | |
| SCHEMBL31415980 | 0.87 | MAPT (0.61) | MAPTALDH1A1TP53HPGDTDP1 | |
| SCHEMBL10779468 | 0.79 | DAO (0.59) | MAPTALDH1A1TP53HPGDTDP1 | |
| SCHEMBL31285969 | 0.75 | HCAR2 (0.53) | MAPTALDH1A1TP53HPGDTDP1 | |
| SCHEMBL15432188 | 0.73 | KMT2A (0.52) | MAPTALDH1A1TP53HPGDTDP1 | |
| SCHEMBL7476495 | 0.72 | ALDH1A1 (0.68) | MAPTALDH1A1TP53HPGDTDP1 | |
| SCHEMBL861728 | 0.72 | MAPT (1.00) | MAPTALDH1A1TP53HPGDTDP1 | |
| SCHEMBL861729 | 0.72 | MAPT (1.00) | MAPTALDH1A1TP53HPGDTDP1 | |
| SCHEMBL7476500 | 0.72 | ALDH1A1 (0.68) | MAPTALDH1A1TP53HPGDTDP1 | |
| SCHEMBL12722253 | 0.71 | MAPT (0.57) | MAPTALDH1A1TP53HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569356-B2 | Cyclin dependent kinase inhibitors | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569356-B2 | Cyclin dependent kinase inhibitors | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20100035940-A1 | Cyclin Dependent Kinase Inhibitors | UNIVERSITY OF FLORDIA RESEARCH FOUNDATION (US) | 2010-02-11 | — | — | US | disclosed |
| US-20100035940-A1 | Cyclin Dependent Kinase Inhibitors | UNIVERSITY OF FLORDIA RESEARCH FOUNDATION (US) | 2010-02-11 | — | — | US | disclosed |
| WO-2007050673-A2 | CYCLIN DEPENDENT KINASE INHIBITORS | UNIVERSITY OF FLORIDA (US) | 2007-05-03 | — | — | WO | disclosed |
| EP-0662968-B1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES INC (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0662968-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1995-07-19 | — | — | EP | disclosed |
| EP-0662968-A4 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS. | PPG INDUSTRIES INC (US) | 1995-04-12 | — | — | EP | disclosed |
| WO-1994007889-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1994-04-14 | — | — | WO | disclosed |
| US-5274132-A | Photochromic naphthopyran compounds | TRANSITIONS OPTICAL, INC. (US) | 1993-12-28 | — | — | US | disclosed |
| US-4939165-A | Miticides | FMC CORPORATION | 1990-07-03 | — | — | US | disclosed |
| EP-0219525-A1 | PHOTOACTIVE BITHIENYL PESTICIDES | FMC Corporation (US) | 1987-04-29 | — | — | EP | disclosed |
| WO-1986005949-A1 | PHOTOACTIVE BITHIENYL PESTICIDES | FMC CORPORATION (US) | 1986-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035940-A1 | Cyclin Dependent Kinase Inhibitors | CCNI, CCNK, CDK1 | MAPT 3256/4885ALDH1A1 3139/4885TP53 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.