Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512916 | 1.00 | PLCG1 (0.81) | PLCG1ALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL8664798 | 1.00 | PLCG1 (0.81) | PLCG1ALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL9623844 | 0.91 | PLCG1 (0.80) | PLCG1ALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL9623847 | 0.91 | PLCG1 (0.80) | PLCG1ALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL8766584 | 0.91 | PLCG1 (0.83) | PLCG1ALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL8766580 | 0.91 | PLCG1 (0.83) | PLCG1ALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL28528206 | 0.91 | PLCG1 (0.83) | PLCG1ALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL11880315 | 0.90 | PLCG1 (0.68) | PLCG1ALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL8664694 | 0.90 | PLCG1 (0.67) | PLCG1ALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL11674207 | 0.90 | PLCG1 (0.67) | PLCG1ALDH1A1L3MBTL1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745603-B1 | Process for p-nitrobenzyl ester cleavage in cephalosporin | RANBAXY LAB LTD (IN) | 1998-12-02 | — | — | EP | disclosed |
| EP-0745603-A1 | Process for p-nitrobenzyl ester cleavage in cephalosporin | Ranbaxy Laboratories Limited (IN) | 1996-12-04 | — | — | EP | disclosed |
| US-5536830-A | Process for P-nitrobenzyl ester cleavage in cephalosporin | RANBAXY LABORATORIES, LTD. (IN) | 1996-07-16 | — | — | US | disclosed |
| US-5532353-A | Process for the preparation of halogenated β-lactam compounds | BIOCHIMICA OPOS SPA (IT) | 1996-07-02 | — | — | US | disclosed |
| EP-0570058-A2 | Process for the preparation of halogenated beta-lactam compounds | BIOCHIMICA OPOS SPA (IT) | 1993-11-18 | — | — | EP | disclosed |
| EP-0015079-B1 | HALOGENATING COMPOUNDS AND A PROCESS FOR THEIR PRODUCTION | ELI LILLY AND COMPANY (US) | 1987-09-09 | — | — | EP | disclosed |
| US-4281116-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4260745-A | 3-Halo cephalosporins | ELI LILLY AND COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4252950-A | ANTIBIOTICS, BACTERICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
| US-4230644-A | DERIVED FROM TRIARYL PHOSPHITES AND CHLORINE OR BROMINE | ELI LILLY AND COMPANY (US) | 1980-10-28 | — | — | US | disclosed |
| US-4208515-A | 3-Halo cephalosporins | ELI LILLY AND COMPANY (US) | 1980-06-17 | — | — | US | disclosed |
| US-4091214-A | ALPHA-HYDROXY CARBOXYLIC ACID | ELI LILLY AND COMPANY (US) | 1978-05-23 | — | — | US | disclosed |
| US-4064343-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-3962227-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |