Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30294755 | 0.85 | ALDH1A1 (0.50) | ALDH1A1GAAPOLBTHRBHPGD | |
| SCHEMBL3030351 | 0.85 | ALDH1A1 (0.52) | ALDH1A1GAAPOLBTHRBEPHX2 | |
| SCHEMBL15512481 | 0.83 | GAA (0.48) | ALDH1A1GAAPOLBTHRBHPGD | |
| SCHEMBL27719541 | 0.83 | THRB (0.45) | ALDH1A1GAAPOLBTHRBNPC1 | |
| SCHEMBL2317882 | 0.82 | KMT2A (0.52) | ALDH1A1HPGDCYP3A4MAPK1NPC1 | |
| SCHEMBL17766955 | 0.81 | MAOB (0.54) | ALDH1A1HPGDCYP3A4MAPK1EPHX2 | |
| SCHEMBL30557826 | 0.81 | MAOB (0.54) | ALDH1A1HPGDCYP3A4MAPK1EPHX2 | |
| SCHEMBL2325383 | 0.81 | ALDH1A1 (0.64) | ALDH1A1HPGDCYP3A4MAPK1NPC1 | |
| SCHEMBL30601548 | 0.80 | ALDH1A1 (0.67) | ALDH1A1GAAHPGDCYP3A4MAPK1 | |
| SCHEMBL898467 | 0.80 | ALDH1A1 (0.67) | ALDH1A1GAAHPGDCYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |
| CN-1277605-A | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2000-12-20 | — | — | CN | disclosed |
| EP-0881220-A1 | DIARYLSULTAM DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-12-02 | — | — | EP | disclosed |