Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663270 | 0.88 | HIF1A (0.49) | ALDH1A1HTTLMNATSHRHIF1A | |
| SCHEMBL13576772 | 0.78 | HIF1A (0.41) | ALDH1A1LMNAHIF1ASMN1; SMN2KDM4E | |
| SCHEMBL17454454 | 0.78 | FAAH (0.54) | ALDH1A1HIF1ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL4503642 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HTTLMNATSHRHIF1A | |
| SCHEMBL2710678 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HTTLMNATSHRHIF1A | |
| SCHEMBL6990506 | 0.75 | BRD4 (0.49) | ALDH1A1HTTLMNATSHRSMN1; SMN2 | |
| SCHEMBL23115220 | 0.75 | MAPT (0.68) | ALDH1A1HTTLMNATSHRSMN1; SMN2 | |
| SCHEMBL11798029 | 0.74 | MAPT (0.51) | ALDH1A1HTTLMNATSHRSMN1; SMN2 | |
| SCHEMBL29652612 | 0.73 | ALDH1A1 (0.47) | ALDH1A1HTTLMNATSHRSMN1; SMN2 | |
| SCHEMBL6955470 | 0.73 | ALDH1A1 (0.47) | ALDH1A1HTTLMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786374-A | FUNGICIDES, MICROBIOCIDES | NOVARTIS CORPORATION (US) | 1998-07-28 | — | — | US | disclosed |
| WO-1996014305-A1 | BENZISOXAZOLE DERIVATIVES AND PESTICIDAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 1996-05-17 | — | — | WO | disclosed |