Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27776903 | 0.83 | TP53 (0.47) | CNR2CNR1CHEK1MAP4K4ABL1 | |
| SCHEMBL7208738 | 0.81 | GRIN2D (0.41) | FLT3HPGDALDH1A1 | |
| SCHEMBL1564392 | 0.81 | GRIN2D (0.41) | FLT3HPGDALDH1A1 | |
| SCHEMBL7922907 | 0.80 | CNR2 (0.41) | CNR2CNR1CHEK1MAP4K4ABL1 | |
| SCHEMBL7922906 | 0.80 | CNR2 (0.41) | CNR2CNR1CHEK1MAP4K4ABL1 | |
| SCHEMBL307118 | 0.76 | ALDH1A1 (0.45) | CNR2CNR1CHEK1MAP4K4ABL1 | |
| SCHEMBL28414965 | 0.74 | ACHE (0.55) | CNR2CNR1CHEK1MAP4K4ABL1 | |
| SCHEMBL18787990 | 0.74 | BACE1 (0.39) | FLT3HPGDALDH1A1MAOB | |
| SCHEMBL24689747 | 0.72 | ACHE (0.52) | CNR2CNR1CHEK1MAP4K4ABL1 | |
| SCHEMBL9807162 | 0.71 | GRIN2D (0.33) | HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796267-B1 | IMPROVED PREPARATION OF TITANIUM(II) OR ZIRCONIUM(II) COMPLEXES | DOW CHEMICAL CO (US) | 1998-12-02 | — | — | EP | claimed |