⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5350956 | 0.78 | HSPA5 (0.38) | — | |
| SCHEMBL10535009 | 0.78 | — | — | |
| SCHEMBL179864 | 0.78 | — | — | |
| SCHEMBL2223002 | 0.77 | HSPA5 (0.46) | — | |
| SCHEMBL5869932 | 0.77 | TAAR1 (0.35) | — | |
| SCHEMBL525380 | 0.74 | — | — | |
| SCHEMBL864779 | 0.72 | — | — | |
| SCHEMBL10719547 | 0.72 | LIPG (0.34) | — | |
| SCHEMBL4650175 | 0.72 | — | — | |
| SCHEMBL232082 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104822380-B | The novel disubstituted aminopyridine derivative of 4,6- | 维罗斯塔蒂克斯公司 | 2019-01-01 | — | — | CN | claimed |
| CN-104822380-B | The novel disubstituted aminopyridine derivative of 4,6- | 维罗斯塔蒂克斯公司 | 2019-01-01 | — | — | CN | disclosed |
| CN-108137515-A | Hydroxy triazine compound and medical use thereof | 日本烟草产业株式会社 | 2018-06-08 | — | — | CN | disclosed |
| CN-107141288-A | One class evodia rutaecarpa alkaloid compound and preparation method and application | 中山大学 | 2017-09-08 | — | — | CN | disclosed |
| CN-104334527-B | Sulfonamide compounds and uses as tnap inhibitors | 桑福德-伯纳姆医学研究院 | 2017-05-24 | — | — | CN | disclosed |
| CN-106243012-A | New indole analog derivative and preparation method thereof | 北方民族大学 | 2016-12-21 | — | — | CN | disclosed |
| CN-102007105-B | 3-aminoalkyl-1, 4-diazepan-2-one melanocortin-5 receptor antagonists | MIMETICA PTY LTD | 2014-09-03 | — | — | CN | disclosed |
| CN-102007106-B | 3-substituted-1,4-diazepan-2-one melanocortin-5 receptor antagonists | MIMETICA PTY LTD | 2014-09-03 | — | — | CN | disclosed |
| CN-102006873-B | Methods of modulating the activity of the mc5 receptor and treatment of conditions related to this receptor | MIMETICA PTY LTD | 2013-09-18 | — | — | CN | disclosed |
| CN-102006873-A | Methods of modulating the activity of the mc5 receptor and treatment of conditions related to this receptor | MIMETICA PTY LTD | 2011-04-06 | — | — | CN | disclosed |
| CN-102007105-A | 3-aminoalkyl-1, 4-diaza-2-one melanocortin-5 receptor antagonists | MIMETICA PTY LTD | 2011-04-06 | — | — | CN | disclosed |
| CN-102007106-A | 3-substituted-1,4-diazepan-2-one melanocortin-5 receptor antagonists | MIMETICA PTY LTD | 2011-04-06 | — | — | CN | disclosed |
| CN-100528872-C | Tetrahydro-proto-berberine compounds, their preparing method, composition and use | SHANGHAI MEDICINE INST CAS (CN) | 2009-08-19 | — | — | CN | disclosed |
| CN-1233176-A | Substituted tricyclics | LILLY CO ELI (US) | 1999-10-27 | — | — | CN | disclosed |
| EP-0880503-A1 | BALANOL ANALOGUES | Phytera Symbion ApS (DK) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997029091-A1 | BALANOL ANALOGUES | PHYTERA SYMBION APS (DK) | 1997-08-14 | — | — | WO | disclosed |