Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3109102 | 0.87 | MAOB (0.53) | MAOBTNFNOD2NOD1ALOX5 | |
| SCHEMBL7353198 | 0.86 | MAOB (0.51) | MAOBTNFNOD2NOD1ALOX5 | |
| SCHEMBL8663594 | 0.85 | MAOB (0.50) | MAOBTNFNOD2NOD1ALOX5 | |
| Potassium Ion SCHEMBL8663591 | 0.85 | MAOB (0.50) | MAOBTNFNOD2NOD1ALOX5 | |
| SCHEMBL31518304 | 0.80 | TRPV4 (0.57) | TRPV4SMN1; SMN2CA1CA2CA9 | |
| SCHEMBL29482639 | 0.78 | TRPV4 (0.68) | TRPV4CA12CA1CA2CA7 | |
| SCHEMBL74997 | 0.78 | TRPV4 (0.68) | TRPV4CA12CA1CA2CA7 | |
| SCHEMBL12473745 | 0.78 | MAOB (0.58) | MAOBALOX5SMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL21327259 | 0.78 | MAOB (0.58) | MAOBALOX5SMN1; SMN2L3MBTL1PDGFRB | |
| SCHEMBL12473744 | 0.78 | MAOB (0.58) | MAOBALOX5SMN1; SMN2RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849780-A | 1-benzenesulfonyl-1-1,3-dihydroindol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present | SANOFI (FR) | 1998-12-15 | — | — | US | disclosed |
| US-5728723-A | ANTIDIURETIC AND OXYTOCIN RECEPTORS | SANOFI (FR) | 1998-03-17 | — | — | US | disclosed |
| US-5726322-A | 1-benzenesulfonyl-1,3-dihydroindol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present | SANOFI (FR) | 1998-03-10 | — | — | US | disclosed |
| US-5686624-A | 1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present | SANOFI (FR) | 1997-11-11 | — | — | US | disclosed |
| US-5663431-A | CHEMICAL INTERMEDIATES | SANOFI (FR) | 1997-09-02 | — | — | US | disclosed |