Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.68 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29482639 | 1.00 | TRPV4 (0.68) | TRPV4CA12CA1CA2CA7 | |
| SCHEMBL29482636 | 0.85 | L3MBTL1 (0.64) | TRPV4CA12CA1CA2CA7 | |
| SCHEMBL407215 | 0.85 | L3MBTL1 (0.64) | TRPV4CA12CA1CA2CA7 | |
| SCHEMBL2494884 | 0.83 | TRPV4 (0.49) | TRPV4CA12CA1CA2CA7 | |
| SCHEMBL2497225 | 0.83 | TRPV4 (0.49) | TRPV4CA12CA1CA2CA7 | |
| SCHEMBL2502219 | 0.83 | TRPV4 (0.57) | TRPV4GAAALPL | |
| SCHEMBL2498920 | 0.83 | TRPV4 (0.57) | TRPV4GAAALPLMMP7 | |
| SCHEMBL31518304 | 0.83 | TRPV4 (0.57) | TRPV4CA1CA2CA9L3MBTL1 | |
| SCHEMBL2719702 | 0.82 | CA12 (0.54) | TRPV4CA12CA1CA2CA7 | |
| SCHEMBL533956 | 0.81 | TRPV4 (0.68) | TRPV4CA1CA2CA9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 388 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104678028-A | Pretreatment and detection method for biogen amine neurotransmitter and detection kit | INST PHARM & TOXICOLOGY AMMS | 2015-06-03 | — | — | CN | claimed |
| EP-4743176-A1 | DEUTERATED 1,3 DIHYDRO -2H-INDOLE-2-ONE DERIVATIVES | HMNC Holding GmbH (DE) | 2026-05-20 | — | — | EP | disclosed |
| EP-4168399-B1 | COMPOUNDS AND THEIR USES AS MIF INHIBITORS | NANJING IMMUNOPHAGE BIOMEDICAL CO LTD (CN) | 2026-04-01 | — | — | EP | disclosed |
| US-20260062393-A1 | Compounds | CTXT PTY LTD (AU) | 2026-03-05 | — | — | US | disclosed |
| US-12479842-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | UNIVERSITE DE MONTREAL (CA) | 2025-11-25 | — | — | US | disclosed |
| US-20250270207-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | UNIVERSITE DE MONTREAL (CA) | 2025-08-28 | — | — | US | disclosed |
| US-12365655-B2 | Compounds | CTXT PTY LTD (AU) | 2025-07-22 | — | — | US | disclosed |
| US-20250122182-A1 | MYST Inhibitors | Isosterix, Inc. | 2025-04-17 | — | — | US | disclosed |
| CN-119462588-A | Flavone derivative containing sulfonamide structure and preparation method and application thereof | 上海中医药大学附属曙光医院 | 2025-02-18 | — | — | CN | disclosed |
| US-20250034117-A1 | Deuterated 1,3 Dihydro -2H-indole-2-one derivatives | HMNC Holding GmbH (DE) | 2025-01-30 | — | — | US | disclosed |
| US-5481005-A | N-sulfonylindoline derivatives, their preparation and the pharmaceutical compositions in which they are present | SANOFI (FR) | 1996-01-02 | — | — | US | disclosed |
| CN-1107467-A | 1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present | SANOFI SA (FR) | 1995-08-30 | — | — | CN | disclosed |
| US-5397801-A | Affinity for vasopressin and ocytocin receptors; disorders of nervous, cardiovascular and gastrointestinal systems | SANOFI (FR) | 1995-03-14 | — | — | US | disclosed |
| US-5338755-A | Have affinity for vasopressin and ocytocin receptors; intermediates for drugs that act on central nervous system | ELF SANOFI (FR) | 1994-08-16 | — | — | US | disclosed |
| US-4714700-A | TRANQUILIZERS, ANXIOLYTIC AGENTS | CHOAY S.A. (FR) | 1987-12-22 | — | — | US | disclosed |
| US-4618459-A | INTERMEDIATES FOR BENZENESULFONAMIDE DERIVATIVES; ANTIDEPRESSANTS | CHOAY S.A. (FR) | 1986-10-21 | — | — | US | disclosed |
| US-4457875-A | ANTIDEPRESSANTS, TRANQUILIZERS | CHOAY S.A. (FR) | 1984-07-03 | — | — | US | disclosed |
| EP-0056274-B1 | INDOLE DERIVATIVES AND A METHOD FOR PRODUCTION OF PEPTIDES | Takeda Chemical Industries, Ltd. (JP) | 1984-05-09 | — | — | EP | disclosed |
| US-4416820-A | Indole derivatives and a method for production of peptides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-11-22 | — | — | US | disclosed |
| EP-0056274-A1 | Indole derivatives and a method for production of peptides | Takeda Chemical Industries, Ltd. (JP) | 1982-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270207-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | BRAF, NRAS, KRAS | TRPV4 3761/4885CA12 4806/4885CA1 4840/4885 |
| US-20260062393-A1 | Compounds | SCN2B, ABCB11, SCN1B | TRPV4 1449/4885CA12 906/4885CA1 1778/4885 |
| US-20250034117-A1 | Deuterated 1,3 Dihydro -2H-indole-2-one derivatives | IDO1, IDO2, TPH1 | TRPV4 1518/4885CA12 1624/4885CA1 1367/4885 |
| US-12479842-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | BRAF, NRAS, DPYD | TRPV4 3686/4885CA12 4810/4885CA1 4841/4885 |
| US-20250122182-A1 | MYST Inhibitors | MNAT1, SUGT1, ACAT2 | TRPV4 4752/4885CA12 4788/4885CA1 4866/4885 |
| US-12365655-B2 | Compounds | SLC10A1, ABCB11, PCSK9 | TRPV4 909/4885CA12 365/4885CA1 881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.