Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | GHSR | Q92847 | 1/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.55 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.52 |
| ▸ | PYGL | P06737 | 1/20 | 0.50 |
| ▸ | PYGM | P11217 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | XIAP | P98170 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665576 | 0.90 | GHSR (0.54) | AGTR1GHSRSCN9ARIPK1MME | |
| SCHEMBL9024198 | 0.85 | XIAP (0.66) | AGTR1GHSRMMEACEXIAP | |
| SCHEMBL9025296 | 0.85 | GHSR (0.68) | AGTR1GHSRMMEACEXIAP | |
| SCHEMBL8670502 | 0.84 | SCN9A (0.55) | GHSRSCN9ARIPK1PYGLPYGM | |
| SCHEMBL9025003 | 0.84 | XIAP (0.67) | AGTR1GHSRMMEACEXIAP | |
| SCHEMBL9025297 | 0.82 | GHSR (0.71) | AGTR1GHSRMMEACEXIAP | |
| SCHEMBL3924251 | 0.81 | RIPK1 (0.63) | SCN9ARIPK1PYGLPYGMMME | |
| SCHEMBL4218830 | 0.81 | RIPK1 (0.63) | SCN9ARIPK1PYGLPYGMMME | |
| SCHEMBL14376829 | 0.81 | RIPK1 (0.60) | SCN9ARIPK1PYGLPYGMMME | |
| SCHEMBL12376364 | 0.80 | SCN9A (0.69) | SCN9ARIPK1PYGLPYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726307-A | Benzo-fused lactams promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |