Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664004 | 0.82 | ALOX5 (0.54) | NPC1RAB9AEPHX2ALOX5MAPT | |
| SCHEMBL8663612 | 0.82 | EPHX2 (0.53) | NPC1RAB9AEPHX2ALOX5MAPT | |
| SCHEMBL8664251 | 0.82 | ALOX5 (0.50) | NPC1RAB9AEPHX2ALOX5MAPT | |
| SCHEMBL8668195 | 0.81 | NPC1 (0.53) | NPC1RAB9AEPHX2ALOX5MAPT | |
| SCHEMBL8665897 | 0.81 | MAPT (0.53) | NPC1RAB9AEPHX2ALOX5MAPT | |
| SCHEMBL8668165 | 0.80 | ALOX5 (0.55) | NPC1RAB9AEPHX2ALOX5MAPT | |
| SCHEMBL7545580 | 0.79 | ALOX5 (0.54) | NPC1RAB9AEPHX2ALOX5MAPT | |
| SCHEMBL8666755 | 0.78 | NPC1 (0.54) | NPC1RAB9AEPHX2ALOX5MAPT | |
| SCHEMBL8664403 | 0.78 | EPHX2 (0.47) | NPC1RAB9AEPHX2ALOX5MAPT | |
| SCHEMBL8668510 | 0.78 | EPHX2 (0.52) | NPC1RAB9AEPHX2ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |