Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663612 | 0.90 | EPHX2 (0.53) | MAPTNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL8668195 | 0.86 | NPC1 (0.53) | MAPTNPC1RAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL8664251 | 0.83 | ALOX5 (0.50) | MAPTNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL8664004 | 0.82 | ALOX5 (0.54) | MAPTNPC1RAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL7548146 | 0.81 | ALOX5 (0.54) | MAPTNPC1RAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL8665596 | 0.81 | NPC1 (0.49) | MAPTNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL7542386 | 0.80 | ALOX5 (0.54) | MAPTNPC1RAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL8668510 | 0.80 | EPHX2 (0.52) | MAPTNPC1RAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL8664403 | 0.80 | EPHX2 (0.47) | MAPTNPC1RAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL7541445 | 0.79 | ALOX5 (0.51) | MAPTNPC1RAB9ASMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |