Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36033 | 0.83 | GAA (0.47) | GAAALDH1A1CYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL29358077 | 0.83 | GAA (0.47) | GAAALDH1A1CYP3A4SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL28434861 | 0.82 | ALDH1A1 (0.47) | GAAALDH1A1CYP3A4SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL6573892 | 0.82 | ALDH1A1 (0.47) | GAAALDH1A1CYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL8484813 | 0.81 | GAA (0.52) | GAAALDH1A1CYP3A4SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL8665041 | 0.80 | ALDH1A1 (0.49) | GAAALDH1A1CYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL6574960 | 0.79 | DHFR (0.38) | GAAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL6573435 | 0.79 | MAPT (0.42) | GAAALDH1A1CYP3A4KDM4EMAPT | |
| SCHEMBL8770011 | 0.79 | GAA (0.46) | GAAALDH1A1CYP3A4SMN1; SMN2KDM4E | |
| SCHEMBL6573021 | 0.78 | ALDH1A1 (0.40) | ALDH1A1CYP3A4SMN1; SMN2KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795313-A2 | Agent and process for oxidative dyeing of keratin fibres | Wella Aktiengesellschaft (DE) | 1997-09-17 | — | — | EP | claimed |
| US-5849041-A | Oxidation hair dye composition and method of dyeing hair using same | WELLA AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0795313-A2 | Agent and process for oxidative dyeing of keratin fibres | Wella Aktiengesellschaft (DE) | 1997-09-17 | — | — | EP | disclosed |