Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9452451 | 0.85 | MAPT (0.66) | MAPTPTGS1SLC6A2MEN1KMT2A | |
| SCHEMBL11667770 | 0.83 | ADRB2 (0.88) | MAPTPTGS1SLC6A2ADRB2ADRB1 | |
| SCHEMBL10792807 | 0.82 | ADRB1 (0.67) | MEN1KMT2AADRB2ADRB1CYP2D6 | |
| SCHEMBL7266770 | 0.82 | PTGS1 (0.68) | MAPTPTGS1SLC6A2MEN1KMT2A | |
| SCHEMBL29358069 | 0.82 | ADRB2 (0.76) | MAPTPTGS1SLC6A2MEN1KMT2A | |
| SCHEMBL11576265 | 0.82 | PTGS1 (0.68) | MAPTPTGS1SLC6A2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10790452 | 0.81 | ADRB1 (0.66) | MAPTMEN1KMT2AADRB2ADRB1 | |
| SCHEMBL10789731 | 0.81 | ADRB1 (0.70) | MEN1KMT2AADRB2ADRB1CYP2D6 | |
| SCHEMBL10791057 | 0.81 | ADRB1 (0.73) | MEN1KMT2AADRB2ADRB1CYP2D6 | |
| SCHEMBL11096422 | 0.81 | PTGS1 (0.67) | MAPTPTGS1SLC6A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767778-B1 | 1-PHENOXY-3-N-ALKYLAMINOPROPAN-2-OL HALOGEN DERIVATIVES USEFUL AS MYOCARDIAL beta ADRENERGIC RECEPTOR MARKERS AND AS beta-BLOCKING AGENTS | CIS BIO INT (FR) | 1998-12-16 | — | — | EP | claimed |
| EP-0767778-A1 | 1-PHENOXY-3-N-ALKYLAMINOPROPAN-2-OL HALOGEN DERIVATIVES USEFUL AS MYOCARDIAL $g(b) ADRENERGIC RECEPTOR MARKERS AND AS $g(b)-BLOCKING AGENTS | CIS BIO INTERNATIONAL (FR) | 1997-04-16 | — | — | EP | claimed |
| WO-1996000717-A1 | 1-PHENOXY-3-N-ALKYLAMINOPROPAN-2-OL HALOGEN DERIVATIVES USEFUL AS MYOCARDIAL β ADRENERGIC RECEPTOR MARKERS AND AS β-BLOCKING AGENTS | CIS BIO INTERNATIONAL (FR) | 1996-01-11 | — | — | WO | claimed |
| WO-1999031072-A1 | CYCLOHEXYLAMINE ARTHROPODICIDES AND FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-06-24 | — | — | WO | disclosed |
| EP-0767778-B1 | 1-PHENOXY-3-N-ALKYLAMINOPROPAN-2-OL HALOGEN DERIVATIVES USEFUL AS MYOCARDIAL beta ADRENERGIC RECEPTOR MARKERS AND AS beta-BLOCKING AGENTS | CIS BIO INT (FR) | 1998-12-16 | — | — | EP | disclosed |
| EP-0767778-A1 | 1-PHENOXY-3-N-ALKYLAMINOPROPAN-2-OL HALOGEN DERIVATIVES USEFUL AS MYOCARDIAL $g(b) ADRENERGIC RECEPTOR MARKERS AND AS $g(b)-BLOCKING AGENTS | CIS BIO INTERNATIONAL (FR) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000717-A1 | 1-PHENOXY-3-N-ALKYLAMINOPROPAN-2-OL HALOGEN DERIVATIVES USEFUL AS MYOCARDIAL β ADRENERGIC RECEPTOR MARKERS AND AS β-BLOCKING AGENTS | CIS BIO INTERNATIONAL (FR) | 1996-01-11 | — | — | WO | disclosed |