Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.44 |
| ▸ | PPARG | P37231 | 15/20 | 0.44 |
| ▸ | PPARA | Q07869 | 14/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559946 | 0.77 | PPARD (0.72) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7039487 | 0.76 | PPARD (0.42) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL8668863 | 0.76 | PPARA (0.49) | PPARDPPARGPPARA | |
| SCHEMBL7046131 | 0.74 | PPARG (0.73) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6559367 | 0.73 | PPARG (0.47) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7041401 | 0.71 | HPSE (0.43) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6932993 | 0.71 | PPARG (0.49) | PPARDPPARGPPARALTB4RLTB4R2 | |
| SCHEMBL8668094 | 0.70 | GRM2 (0.36) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL8443121 | 0.70 | KDM1A (0.43) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7039181 | 0.70 | PPARD (0.62) | PPARDPPARGPPARANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882029-A1 | HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | Merck & Co., Inc. (US) | 1998-12-09 | — | — | EP | claimed |
| WO-1997028137-A1 | HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | claimed |