Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 16/20 | 0.42 |
| ▸ | PPARG | P37231 | 15/20 | 0.42 |
| ▸ | PPARA | Q07869 | 15/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039487 | 0.75 | PPARD (0.42) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7046131 | 0.75 | PPARG (0.73) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL8444660 | 0.75 | LTB4R (0.37) | PPARDPPARGPPARALTB4RLTB4R2 | |
| SCHEMBL6559946 | 0.75 | PPARD (0.72) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6932993 | 0.73 | PPARG (0.49) | PPARDPPARGPPARALTB4RLTB4R2 | |
| SCHEMBL7039181 | 0.70 | PPARD (0.62) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7040305 | 0.70 | NR1H3 (0.81) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL8666064 | 0.70 | PPARD (0.44) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6559367 | 0.69 | PPARG (0.47) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7041401 | 0.67 | HPSE (0.43) | PPARDPPARGPPARANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904079-A4 | — | — | 1999-05-06 | — | — | EP | claimed |
| EP-0904079-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-03-31 | — | — | EP | claimed |
| WO-1997027857-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | claimed |
| EP-0904079-A4 | — | — | 1999-05-06 | — | — | EP | disclosed |
| EP-0904079-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-03-31 | — | — | EP | disclosed |
| US-5859051-A | ACETYLPHENOL DERIVATIVES | MERCK & CO., INC. (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1997027857-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |