SCHEMBL8666249

SCHEMBL8666249

CCCCc1cccc2c1C(=O)C(O)(C(=O)O)C2=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 6/20 0.43
MCL1 Q07820 6/20 0.43
BCL2L1 Q07817 5/20 0.43
BAK1 Q16611 5/20 0.43
PPARA Q07869 3/20 0.43
KAT8 Q9H7Z6 2/20 0.43
PPARG P37231 2/20 0.43
SAE1 Q9UBE0 2/20 0.43
EP300 Q09472 1/20 0.43
KAT2A Q92830 1/20 0.43
KAT2B Q92831 1/20 0.43
KAT5 Q92993 1/20 0.43
ELANE P08246 4/20 0.41
CTSG P08311 4/20 0.41
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
CYSLTR2 Q9NS75 1/20 0.39
CYSLTR1 Q9Y271 1/20 0.39
MMP2 P08253 2/20 0.38
F7 P08709 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2958940 0.85 ELANE (0.41) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL2956670 0.84 ELANE (0.39) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL2947351 0.83 ELANE (0.41) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL419673 0.83 ELANE (0.45) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL2954201 0.82 PPARA (0.45) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL2955871 0.81 ELANE (0.43) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL2955906 0.80 ELANE (0.47) BIDMCL1BCL2L1BAK1PPARA
SCHEMBL2947713 0.78 ELANE (0.45) PPARAPPARGELANECTSGMAPT
SCHEMBL2947469 0.76 ALDH1A1 (0.39) ELANECTSGKDM4EMAPT
SCHEMBL1879231 0.75 THRB (0.54) BIDMCL1BCL2L1BAK1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0594290-B1 Ceramic body and method and apparatus for detecting change thereof HITACHI LTD (JP) 1998-12-09 EP disclosed
US-5581039-A Ceramic body and method and apparatus for detecting change thereof HITACHI, LTD. (JP) 1996-12-03 US disclosed
EP-0594290-A1 Ceramic body and method and apparatus for detecting change thereof HITACHI, LTD. (JP) 1994-04-27 EP disclosed