SCHEMBL8666258

SCHEMBL8666258

Cc1ccc(S(=O)(=O)NC=O)cc1.c1ncncn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.50
GAA P10253 2/20 0.50
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
MMP1 P03956 1/20 0.48
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48
MMP8 P22894 1/20 0.48
MMP13 P45452 1/20 0.48
CYP2C9 P11712 4/20 0.47
CYP2C19 P33261 4/20 0.47
CA12 O43570 2/20 0.47
CA9 Q16790 2/20 0.47
ALDH1A1 P00352 6/20 0.46
LMNA P02545 2/20 0.45
HTT P42858 1/20 0.45
KDM4E B2RXH2 3/20 0.45
HPGD P15428 3/20 0.45
TDP1 Q9NUW8 3/20 0.45
CYP1A2 P05177 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17764 0.91 GAA (0.59) SMN1; SMN2GAACA1CA2MMP1
SCHEMBL8351001 0.75 GAA (0.59) SMN1; SMN2GAACA1CA2MMP1
SCHEMBL1387778 0.73 GAA (0.57) SMN1; SMN2GAACA1CA2MMP1
SCHEMBL16452382 0.73 GAA (0.57) SMN1; SMN2GAACA1CA2MMP1
SCHEMBL10465574 0.73 GAA (0.57) SMN1; SMN2GAACA1CA2MMP1
SCHEMBL27485095 0.73 GAA (0.57) SMN1; SMN2GAACA1CA2MMP1
SCHEMBL92828 0.72 CA1 (0.56) SMN1; SMN2CA1CA2MMP1MMP2
SCHEMBL13712808 0.72 GAA (0.55) SMN1; SMN2GAACA1CA2MMP1
SCHEMBL28697113 0.72 ALDH1A1 (0.58) SMN1; SMN2GAACA1CA2MMP1
SCHEMBL11751509 0.71 CA1 (0.57) SMN1; SMN2CA1CA2MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0592185-B1 Non aqueous fluorescent dispersion ink PITNEY BOWES INC (US) 1998-12-23 EP claimed
EP-0592185-A1 Non aqueous fluorescent dispersion ink PITNEY BOWES INC. (US) 1994-04-13 EP claimed
US-5290348-A Non aqueous fluorescent dispersion ink with improved shelf life, tack and flow PITNEY BOWES INC. (US) 1994-03-01 US claimed
EP-0592185-B1 Non aqueous fluorescent dispersion ink PITNEY BOWES INC (US) 1998-12-23 EP disclosed