Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654022 | 0.95 | TSHR (0.38) | TSHRSERPINE1PTPN1HDAC3HDAC4 | |
| SCHEMBL7793715 | 0.88 | TSHR (0.40) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7765364 | 0.87 | TSHR (0.33) | TSHR | |
| SCHEMBL22193457 | 0.86 | TSHR (0.33) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22193459 | 0.86 | TSHR (0.39) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22193460 | 0.84 | TSHR (0.31) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7792822 | 0.84 | TSHR (0.45) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7765359 | 0.82 | — | — | |
| SCHEMBL29623140 | 0.82 | THRB (0.41) | TSHRSERPINE1HDAC3HDAC4HDAC1 | |
| SCHEMBL23601572 | 0.80 | TSHR (0.42) | TSHRSERPINE1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780668-A | A CURABLE MONOMER OF A (MONO-, DI- OR TRIACRYLOYLOXY-SUBSTITUTED ALKYLENEAMIDO OR OXYCARBONYL-) -TRIODOBENZENES; REPLACES FILLERS IN CROWNS, BRIDGES ETC.; UV RESISTANCE; STABILITY | IVOCLAR AG (LI) | 1998-07-14 | — | — | US | claimed |