Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666299 | 0.93 | BDKRB2 (0.42) | BDKRB2KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8666404 | 0.93 | SMN1; SMN2 (0.43) | BDKRB2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8666461 | 0.92 | PPARG (0.46) | BDKRB2KDM4ENPC1ALDH1A1 | |
| SCHEMBL8565416 | 0.83 | BDKRB2 (0.58) | BDKRB2 | |
| SCHEMBL8666921 | 0.82 | BDKRB2 (0.50) | BDKRB2 | |
| SCHEMBL8563482 | 0.81 | PPARG (0.42) | — | |
| SCHEMBL8570185 | 0.80 | BDKRB2 (0.43) | BDKRB2 | |
| SCHEMBL8666936 | 0.79 | LMNA (0.44) | BDKRB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8563420 | 0.79 | PPARG (0.46) | — | |
| SCHEMBL8667851 | 0.78 | MEN1 (0.44) | BDKRB2KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750699-A | HALOGENATING OF CORRESPONDING COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |