Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GCGR | P47871 | 1/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | PNLIP | P16233 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4152345 | 0.95 | MEN1 (0.51) | KDM4ENPC1ALDH1A1MAPK1GCGR | |
| SCHEMBL8657651 | 0.90 | GCGR (0.47) | KDM4ENPC1ALDH1A1MAPK1GCGR | |
| SCHEMBL10919264 | 0.89 | GCGR (0.45) | KDM4ENPC1ALDH1A1MAPK1GCGR | |
| SCHEMBL10896474 | 0.89 | GCGR (0.45) | KDM4ENPC1ALDH1A1MAPK1GCGR | |
| SCHEMBL9683664 | 0.87 | MEN1 (0.52) | KDM4ENPC1ALDH1A1MAPK1GCGR | |
| SCHEMBL10943518 | 0.87 | GCGR (0.70) | KDM4ENPC1ALDH1A1MAPK1GCGR | |
| SCHEMBL9134026 | 0.86 | ENPP1 (0.48) | KDM4ENPC1ALDH1A1MAPK1GCGR | |
| SCHEMBL9135290 | 0.86 | ENPP1 (0.48) | KDM4ENPC1ALDH1A1MAPK1GCGR | |
| SCHEMBL8658796 | 0.85 | PNLIP (0.62) | NPC1GCGRTLR8PNLIPPPIA | |
| SCHEMBL8662609 | 0.85 | TLR8 (0.54) | KDM4ENPC1ALDH1A1MAPK1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |