SCHEMBL8666641

SCHEMBL8666641

CC(=O)C(Oc1ccccc1)(C(=O)O)N1CC(=O)N(C2CCNCC2)CC1=O

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 2/20 0.37
SSTR1 P30872 1/20 0.37
PARP1 P09874 1/20 0.34
HRH1 P35367 1/20 0.32
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
HTR4 Q13639 1/20 0.31
SLC6A3 Q01959 1/20 0.31
EPHX1 P07099 1/20 0.31
P2RX7 Q99572 1/20 0.31
NSD3 Q9BZ95 1/20 0.31
KHK P50053 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8670941 0.99 SSTR4 (0.36) SSTR4SSTR1PARP1HRH1SLC6A2
SCHEMBL8670582 0.84 SSTR4 (0.36) SSTR4SSTR1HRH1KHK
SCHEMBL8669845 0.83 TP53 (0.39) SSTR4SSTR1PARP1HRH1EPHX1
Hydrochloric Acid SCHEMBL8670984 0.82 TP53 (0.39) SSTR4SSTR1PARP1HRH1P2RX7
SCHEMBL8668015 0.81 SSTR4 (0.38) SSTR4SSTR1PARP1HRH1SLC6A2
Hydrochloric Acid SCHEMBL8670955 0.80 SSTR4 (0.38) SSTR4SSTR1PARP1HRH1NSD3
SCHEMBL8482988 0.76 SSTR4 (0.39) SSTR4SSTR1HRH1KHK
Hydrochloric Acid SCHEMBL8480749 0.75 SSTR4 (0.39) SSTR4SSTR1HRH1KHK
SCHEMBL8670654 0.72 ITGB3 (0.35) SSTR4SSTR1SLC6A2SLC6A4
Trifluoroacetic Acid SCHEMBL8669184 0.70 ITGB3 (0.34) SSTR4SSTR1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5814636-A TREATMENT AND PROPHYLAXIS OF THROMBOTIC DISEASES MEIJI SEIKA KABUSHIKI KAISHA (JP) 1998-09-29 US disclosed