Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31612522 | 0.86 | ABCB11 (0.44) | ABCB11ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL13814014 | 0.82 | ABCB11 (0.42) | ABCB11ALDH1A1KDM4ETPMTGAA | |
| SCHEMBL31612525 | 0.82 | ABCB11 (0.42) | ABCB11ALDH1A1KDM4ETPMTGAA | |
| SCHEMBL8667615 | 0.79 | ALDH1A1 (0.55) | ABCB11ALDH1A1KDM4ETPMTGAA | |
| SCHEMBL29407367 | 0.76 | ABCB11 (0.38) | ABCB11ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL8640622 | 0.75 | CYP3A4 (0.47) | ALDH1A1KDM4ETPMTGAAHPGD | |
| SCHEMBL4645395 | 0.74 | ABCB11 (0.49) | ABCB11ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL10926373 | 0.73 | ABCB11 (0.53) | ABCB11ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL10518784 | 0.73 | KDM4E (0.45) | ABCB11ALDH1A1KDM4ETPMTGAA | |
| SCHEMBL11245676 | 0.73 | ABCB11 (0.41) | ABCB11ALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739353-A | N-arylindoles and their use as herbicides | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | disclosed |
| EP-0681581-B1 | SUBSTITUTED FUSED PYRAZOLO COMPOUNDS AND THEIR USE AS HERBICIDES | ZENECA LTD (GB) | 1997-09-10 | — | — | EP | disclosed |
| US-5599774-A | PRE- AND POSTEMERGENCE HERBICIDES FOR CROPS, PARTICULARLY CORN, RICE AND SOYBEANS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1997-02-04 | — | — | US | disclosed |
| EP-0681581-A1 | SUBSTITUTED FUSED PYRAZOLO COMPOUNDS AND THEIR USE AS HERBICIDES. | ZENECA LTD (GB) | 1995-11-15 | — | — | EP | disclosed |
| US-5430007-A | Certain herbicidal pyrazolopyridazines | ZENECA LIMITED (GB) | 1995-07-04 | — | — | US | disclosed |
| US-5395817-A | N-pyridine substituted indoles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-03-07 | — | — | US | disclosed |
| EP-0626946-A1 | N-PHENYLINDOLE AND N-PYRIDYLINDOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | ZENECA LIMITED (GB) | 1994-12-07 | — | — | EP | disclosed |
| WO-1994017062-A1 | SUBSTITUTED FUSED PYRAZOLO COMPOUNDS AND THEIR USE AS HERBICIDES | ZENECA LIMITED (GB) | 1994-08-04 | — | — | WO | disclosed |
| US-5300478-A | Herbicides | ZENECA LIMITED (GB) | 1994-04-05 | — | — | US | disclosed |
| WO-1993015049-A1 | N-PHENYLINDOLE AND N-PYRIDYLINDOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | ZENECA LIMITED (GB) | 1993-08-05 | — | — | WO | disclosed |
| US-5232899-A | Applying as pre- and post-emergence herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-03 | — | — | US | disclosed |
| US-5022915-A | Substituted 2,4-diarylpyrimidines and their use as herbicides | ICI AMERICAS INC. (US) | 1991-06-11 | — | — | US | disclosed |