Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | APAF1 | O14727 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | TDP2 | O95551 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665878 | 0.86 | MAPT (0.54) | ADORA1ADORA2AMAPTKMT2AALDH1A1 | |
| SCHEMBL8666248 | 0.86 | MAPT (0.64) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL1822988 | 0.85 | MAPT (0.70) | ADORA1ADORA2AMAPTKMT2AALDH1A1 | |
| SCHEMBL8669412 | 0.84 | MAPT (0.45) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL4957609 | 0.83 | ADORA1 (0.66) | ADORA1ADORA2AMAPTKMT2AALDH1A1 | |
| SCHEMBL4958725 | 0.83 | ADORA1 (0.60) | ADORA1ADORA2AMAPTKMT2AALDH1A1 | |
| SCHEMBL4960241 | 0.82 | ADORA1 (0.61) | ADORA1ADORA2AMAPTKMT2AALDH1A1 | |
| SCHEMBL8667667 | 0.82 | ADORA1 (0.54) | ADORA1ADORA2AMAPTKMT2AALDH1A1 | |
| SCHEMBL4960548 | 0.81 | ADORA1 (0.57) | ADORA1ADORA2AMAPTKMT2AALDH1A1 | |
| SCHEMBL4961540 | 0.80 | KDM4E (0.59) | ADORA1ADORA2AMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638581-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 1998-12-23 | — | — | EP | claimed |