Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 17/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.57 |
| ▸ | TP53 | P04637 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | APAF1 | O14727 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | TDP2 | O95551 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671673 | 0.87 | MAPT (0.63) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL8666934 | 0.86 | ADORA1 (0.55) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL4958350 | 0.83 | MAPT (0.68) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL8669412 | 0.80 | MAPT (0.45) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL8666532 | 0.78 | MAPT (0.52) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL8670643 | 0.77 | MAPT (0.63) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL8665878 | 0.73 | MAPT (0.54) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL7652902 | 0.73 | MAPT (0.53) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL8671324 | 0.72 | MPL (0.47) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| Bromide SCHEMBL7650921 | 0.72 | MAPT (0.53) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638581-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 1998-12-23 | — | — | EP | claimed |