Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.49 |
| ▸ | CTSV | O60911 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12393704 | 0.83 | NQO1 (0.55) | ALDH1A1KDM4EHPGDSMN1; SMN2ABCG2 | |
| SCHEMBL8668538 | 0.81 | ABCG2 (0.62) | ALDH1A1KDM4EHPGDSMN1; SMN2ABCG2 | |
| SCHEMBL12328355 | 0.79 | KDM4E (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL12328354 | 0.79 | KDM4E (0.53) | ALDH1A1KDM4EHPGDSMN1; SMN2PDE3B | |
| SCHEMBL5879177 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDSMN1; SMN2PDE3B | |
| SCHEMBL8667681 | 0.77 | ABCG2 (0.65) | ALDH1A1KDM4EHPGDABCG2HSD17B10 | |
| SCHEMBL8673520 | 0.77 | ABCG2 (0.65) | ALDH1A1KDM4EHPGDABCG2HSD17B10 | |
| SCHEMBL12425672 | 0.77 | ABCG2 (0.49) | ALDH1A1KDM4EHPGDSMN1; SMN2ABCG2 | |
| SCHEMBL8666256 | 0.77 | ABCG2 (0.65) | ALDH1A1KDM4EHPGDABCG2HSD17B10 | |
| SCHEMBL8666512 | 0.77 | ABCG2 (0.65) | ALDH1A1KDM4EHPGDABCG2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649406-B1 | CARBAZOLE DERIVATIVES AND THEIR USE IN COSMETICS, ESPECIALLY FOR MAKE-UP | OREAL (FR) | 1998-12-23 | — | — | EP | claimed |
| US-5543436-A | USED AS PIGMENTS IN COSMETICS, PARTICULARLY INTENDED FOR TREATMENT AND/OR COLORATION OF KERATINOUS SUBSTANCES | L'OREAL (FR) | 1996-08-06 | — | — | US | disclosed |