Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667176 | 1.00 | ESR1 (0.34) | ESR1ESR2ELANEKDM4EALDH1A1 | |
| SCHEMBL9460459 | 0.87 | ELANE (0.43) | ESR1ESR2ELANEKDM4EALDH1A1 | |
| SCHEMBL8668726 | 0.87 | ELANE (0.43) | ESR1ESR2ELANEKDM4EALDH1A1 | |
| SCHEMBL7360743 | 0.80 | KMT2A (0.36) | ESR1ESR2ELANEKDM4EALDH1A1 | |
| SCHEMBL8667175 | 0.80 | ELANE (0.49) | ESR1ESR2ELANE | |
| SCHEMBL9461074 | 0.80 | ELANE (0.49) | ESR1ESR2ELANE | |
| SCHEMBL7360746 | 0.80 | KMT2A (0.36) | ESR1ESR2ELANEKDM4EALDH1A1 | |
| SCHEMBL8668549 | 0.78 | ELANE (0.33) | ELANE | |
| SCHEMBL8668553 | 0.78 | ELANE (0.33) | ELANE | |
| SCHEMBL9637314 | 0.77 | ESR1 (0.38) | ESR1ESR2ELANEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494914-B1 | 2-SPIROCYCLOPROPYL CEPHALOSPORIN DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LAB INC (CA) | 1998-12-23 | — | — | EP | disclosed |
| US-5264430-A | Enzyme inhibitor, antiinflammatory agents, treats emphysema, cystic fibrosis and arthritis | SYNPHAR LABORATORIES, INC. (CA) | 1993-11-23 | — | — | US | disclosed |
| US-5264429-A | Enzyme inhibitor, antiinflammatory agents, treats emphysema, cystic fibrosis and arthritis | SYNPHAR LABORATORIES, INC. (CA) | 1993-11-23 | — | — | US | disclosed |
| WO-1991004977-A1 | NOVEL 2-SPIROCYCLOPROPYL CEPHALOSPORIN SULFONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LABORATORIES, INC. (CA) | 1991-04-18 | — | — | WO | disclosed |