Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635961 | 0.87 | ELANE (0.36) | ESR1ESR2ELANEALDH1A1HPGD | |
| SCHEMBL9635856 | 0.79 | ELANE (0.45) | ESR1ESR2ELANEALDH1A1HPGD | |
| SCHEMBL8669679 | 0.79 | ALDH1A1 (0.51) | ESR1ALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL8669680 | 0.79 | ALDH1A1 (0.51) | ESR1ALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL8667178 | 0.77 | ESR1 (0.34) | ESR1ESR2ELANEALDH1A1HPGD | |
| SCHEMBL8667176 | 0.77 | ESR1 (0.34) | ESR1ESR2ELANEALDH1A1HPGD | |
| SCHEMBL9755490 | 0.77 | MEN1 (0.31) | ESR1HSD17B10KMT2AMAPTSLC15A2 | |
| SCHEMBL9755501 | 0.76 | ELANE (0.39) | ELANECTDSP1 | |
| SCHEMBL9755503 | 0.76 | ELANE (0.39) | ELANECTDSP1 | |
| SCHEMBL11360226 | 0.72 | PTGS1 (0.57) | ESR1ELANEHPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494914-A1 | NOVEL 2-SPIROCYCLOPROPYL CEPHALOSPORIN SULFONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | SYNPHAR LABORATORIES INC. (CA) | 1992-07-22 | — | — | EP | disclosed |