Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MPO | P05164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196594 | 0.89 | ALDH1A1 (0.69) | ALDH1A1MPOKDM4ECHRNA7POLB | |
| SCHEMBL11194277 | 0.87 | ALDH1A1 (0.73) | ALDH1A1MPOKDM4ECHRNA7POLB | |
| SCHEMBL11844158 | 0.79 | MPO (0.70) | ALDH1A1MPOKDM4ELMNAHTT | |
| SCHEMBL28627893 | 0.79 | VEGFA (0.61) | ALDH1A1MPOKDM4ECHRNA7POLB | |
| SCHEMBL22711512 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MPOKDM4ECHRNA7POLB | |
| SCHEMBL10415354 | 0.79 | MPO (0.84) | ALDH1A1MPOKDM4ECHRNA7HRH3 | |
| SCHEMBL1964500 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MPOKDM4ECHRNA7POLB | |
| SCHEMBL17585440 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MPOKDM4ECHRNA7POLB | |
| SCHEMBL7539704 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MPOKDM4ECHRNA7POLB | |
| SCHEMBL10073543 | 0.78 | KDM4E (0.63) | ALDH1A1MPOKDM4ECHRNA7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876347-A1 | QUINOLINE DERIVATIVES | Smithkline Beecham S.p.A. (IT) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997021680-A1 | QUINOLINE DERIVATIVES | SMITHKLINE BEECHAM S.P.A. (IT) | 1997-06-19 | — | — | WO | disclosed |