Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 5/20 | 0.47 |
| ▸ | CES1 | P23141 | 3/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620397 | 1.00 | TRPA1 (0.54) | TRPA1MAPTRXFP1TRPV1FAAH | |
| SCHEMBL9620206 | 0.83 | TRPA1 (0.56) | TRPA1MAPTRXFP1TRPV1FAAH | |
| SCHEMBL14201454 | 0.78 | TRPA1 (0.48) | TRPA1MAPTRXFP1TRPV1FAAH | |
| SCHEMBL10694052 | 0.77 | TRPA1 (0.56) | TRPA1MAPTRXFP1TRPV1FAAH | |
| SCHEMBL8663794 | 0.76 | TRPA1 (0.59) | TRPA1MAPTRXFP1TRPV1FAAH | |
| SCHEMBL11831213 | 0.76 | TRPA1 (0.59) | TRPA1MAPTRXFP1TRPV1FAAH | |
| SCHEMBL11836000 | 0.76 | TRPA1 (0.59) | TRPA1MAPTRXFP1TRPV1FAAH | |
| SCHEMBL5155795 | 0.76 | TRPA1 (0.59) | TRPA1MAPTRXFP1TRPV1FAAH | |
| SCHEMBL8667618 | 0.76 | TRPA1 (0.59) | TRPA1MAPTRXFP1TRPV1FAAH | |
| SCHEMBL864212 | 0.76 | TRPA1 (0.59) | TRPA1MAPTRXFP1TRPV1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728752-A | LACTONE POLYMERS | ETHICON, INC. (US) | 1998-03-17 | — | — | US | disclosed |