Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.71 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | SHBG | P04278 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.55 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | ESRRB | O95718 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038305 | 1.00 | ESR1 (0.71) | ESR1ESR2LMNAHSD17B10TSHR | |
| SCHEMBL8038391 | 1.00 | ESR1 (0.71) | ESR1ESR2LMNAHSD17B10TSHR | |
| SCHEMBL19236350 | 1.00 | ESR1 (0.71) | ESR1ESR2LMNAHSD17B10TSHR | |
| SCHEMBL8048890 | 0.84 | LMNA (0.56) | ESR1ESR2LMNAHSD17B10TSHR | |
| SCHEMBL8048425 | 0.84 | LMNA (0.56) | ESR1ESR2LMNAHSD17B10TSHR | |
| SCHEMBL24051967 | 0.84 | ESR1 (0.67) | ESR1ESR2LMNAHSD17B10TSHR | |
| SCHEMBL8038117 | 0.83 | ESR1 (0.50) | ESR1ESR2LMNAHSD17B10TSHR | |
| SCHEMBL1688726 | 0.81 | ESR1 (0.59) | ESR1ESR2LMNAHSD17B10KMT2A | |
| SCHEMBL1688725 | 0.78 | ESR1 (0.71) | ESR1ESR2LMNAHSD17B10MAPT | |
| Estradiol SCHEMBL18258335 | 0.71 | ESR1 (1.00) | ESR1ESR2LMNAHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882735-A1 | 9 Alpha-hydroxy-8 alpha-estra-1,3,5(10)-trienes and a process for their preparation | Jenapharm GmbH & Co. KG (DE) | 1998-12-09 | — | — | EP | disclosed |