Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671337 | 0.81 | RAB9A (0.53) | NPC1RAB9ALMNAKDM4EPKM | |
| SCHEMBL6525088 | 0.80 | CYSLTR1 (0.52) | LMNACYSLTR2CYSLTR1CYP1A2 | |
| SCHEMBL17227498 | 0.79 | CYSLTR1 (0.50) | NPC1RAB9ALMNAKDM4EPKM | |
| SCHEMBL177539 | 0.79 | RAB9A (0.53) | NPC1RAB9ALMNAKDM4EPKM | |
| SCHEMBL5238162 | 0.77 | CYP1A2 (0.49) | LMNAKDM4ECYSLTR2CYSLTR1CYP1A2 | |
| SCHEMBL1163878 | 0.77 | CYSLTR1 (0.49) | LMNACYSLTR2CYSLTR1CYP1A2 | |
| SCHEMBL322184 | 0.77 | CYSLTR1 (0.49) | LMNACYSLTR2CYSLTR1CYP1A2 | |
| SCHEMBL1777676 | 0.77 | CYSLTR1 (0.49) | LMNACYSLTR2CYSLTR1CYP1A2 | |
| SCHEMBL9287417 | 0.77 | CYP1A2 (0.49) | LMNAKDM4ECYSLTR2CYSLTR1CYP1A2 | |
| SCHEMBL1163276 | 0.77 | NPC1 (0.56) | NPC1RAB9ALMNAKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811422-A | USEFUL FOR TREATING VIRAL INFECTIONS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-09-22 | — | — | US | disclosed |