Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555893 | 0.89 | PLK1 (0.31) | KDM4EUSP2ALDH1A1POLBMAPT | |
| SCHEMBL8664333 | 0.87 | KCNH2 (0.37) | KDM4EALDH1A1HSD17B10TDP1L3MBTL1 | |
| SCHEMBL7770555 | 0.86 | KCNH2 (0.40) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8670473 | 0.86 | KCNH2 (0.40) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8667845 | 0.86 | KCNH2 (0.40) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5892150 | 0.85 | IDO1 (0.34) | USP2RECQL | |
| SCHEMBL5012855 | 0.79 | KEAP1 (0.42) | KDM4EMAPTHSD17B10L3MBTL1 | |
| SCHEMBL2456293 | 0.77 | IDO1 (0.32) | USP2 | |
| SCHEMBL4680152 | 0.76 | TAAR1 (0.31) | — | |
| SCHEMBL7572440 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750552-A | ANTIULCER AGENTS | ARAX CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0736527-A1 | Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer | ARAX CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |