Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29408737 | 0.80 | RXFP1 (0.61) | POLBLMNATSHRSMN1; SMN2KMT2A | |
| SCHEMBL422636 | 0.80 | RXFP1 (0.61) | POLBLMNATSHRSMN1; SMN2KMT2A | |
| SCHEMBL27693763 | 0.79 | SLC40A1 (0.55) | SLC40A1PKMPOLBLMNATSHR | |
| SCHEMBL31309573 | 0.77 | CA1 (0.70) | ALDH1A1HPGDCA1CA2CA9 | |
| SCHEMBL4463532 | 0.77 | CA1 (0.70) | ALDH1A1HPGDCA1CA2CA9 | |
| SCHEMBL6542393 | 0.77 | SLC40A1 (0.60) | SLC40A1POLBLMNATSHRMCL1 | |
| SCHEMBL8667441 | 0.76 | MCL1 (0.58) | SLC40A1PKMPOLBTSHRSMN1; SMN2 | |
| SCHEMBL498547 | 0.75 | ALDH1A1 (0.55) | SLC40A1PKMPOLBLMNATSHR | |
| SCHEMBL1644002 | 0.75 | ALDH1A1 (0.55) | SLC40A1PKMPOLBLMNATSHR | |
| SCHEMBL30673688 | 0.75 | ALDH1A1 (0.55) | SLC40A1PKMPOLBLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0881220-A1 | DIARYLSULTAM DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-12-02 | — | — | EP | disclosed |