Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | DHODH | Q02127 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669727 | 0.81 | DHODH (0.43) | DHODHLMNAPDE10ATSHRLTB4R | |
| SCHEMBL5182384 | 0.81 | PSMB8 (0.40) | PSMB8PSMB5ALDH1A1DHODHPDE10A | |
| SCHEMBL8677313 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1DHODHLMNAPDE10ATSHR | |
| SCHEMBL3075378 | 0.74 | PSMB8 (0.38) | PSMB8PSMB5 | |
| Trifluoromethanesulfonic Acid SCHEMBL7644634 | 0.73 | PSMB8 (0.37) | PSMB8PSMB5 | |
| SCHEMBL21664524 | 0.70 | CDYL (0.49) | PSMB8PSMB5KDM4ECYP1A2 | |
| SCHEMBL3415993 | 0.67 | PSMB8 (0.36) | PSMB8PSMB5 | |
| SCHEMBL1804142 | 0.67 | KMT2A (0.52) | PSMB8PSMB5ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL16624723 | 0.67 | ALDH1A1 (0.41) | PSMB8PSMB5ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3143334 | 0.67 | KDM4E (0.44) | ALDH1A1DHODHLMNAPDE10AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837452-A | HEATING CELLS IN SOLUTION CONTAINING NONIONIC SURFACTANT DETERGENT AND CHELATE COMPOUND | GEN-PROBE INCORPORATED (US) | 1998-11-17 | — | — | US | disclosed |