SCHEMBL8668281

SCHEMBL8668281

CCCC(C1=CC=CC1)C1=CC=CC1.[Zr]

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.31
GPR84 Q9NQS5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6672569 0.98 FFAR1 (0.32) FFAR1GPR84
SCHEMBL6676488 0.85 DNM1 (0.30)
SCHEMBL6677627 0.83 OPRM1 (0.32) FFAR1GPR84
SCHEMBL6911373 0.82 ESR1 (0.31)
SCHEMBL6672780 0.79
SCHEMBL4810874 0.78
SCHEMBL6911851 0.78
SCHEMBL8194965 0.78
SCHEMBL28988062 0.77
SCHEMBL28767803 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5767217-A Process for the preparation of polyorganosiloxanes containing unsaturated functions, by dehydrogenative condensation in the presence of titanium, zirconium or hafnium RHONE-POULENC CHIMIE (FR) 1998-06-16 US claimed
EP-0717757-B1 METHOD FOR THE PREPARATION OF POLYORGANOSILOXANES WITH INSATURATED FUNCTIONS BY DEHYDROGENOCONDENSATION IN THE PRESENCE OF COMPLEXES OF TITANIUM, ZIRKONIUM OR HAFNIUM RHONE POULENC CHIMIE (FR) 1997-12-17 EP claimed
EP-0717757-A1 METHOD FOR THE PREPARATION OF POLYORGANOSILOXANES WITH INSATURATED FUNCTIONS BY DEHYDROGENOCONDENSATION IN THE PRESENCE OF COMPLEXES OF TITANIUM, ZIRKONIUM OR HAFNIUM RHONE-POULENC CHIMIE (FR) 1996-06-26 EP claimed
WO-1995007312-A1 METHOD FOR THE PREPARATION OF POLYORGANOSILOXANES WITH INSATURATED FUNCTIONS BY DEHYDROGENOCONDENSATION IN THE PRESENCE OF COMPLEXES OF METALS OF GROUP IV RHONE-POULENC CHIMIE (FR) 1995-03-16 WO claimed
US-5767217-A Process for the preparation of polyorganosiloxanes containing unsaturated functions, by dehydrogenative condensation in the presence of titanium, zirconium or hafnium RHONE-POULENC CHIMIE (FR) 1998-06-16 US disclosed
EP-0717757-B1 METHOD FOR THE PREPARATION OF POLYORGANOSILOXANES WITH INSATURATED FUNCTIONS BY DEHYDROGENOCONDENSATION IN THE PRESENCE OF COMPLEXES OF TITANIUM, ZIRKONIUM OR HAFNIUM RHONE POULENC CHIMIE (FR) 1997-12-17 EP disclosed
EP-0717757-A1 METHOD FOR THE PREPARATION OF POLYORGANOSILOXANES WITH INSATURATED FUNCTIONS BY DEHYDROGENOCONDENSATION IN THE PRESENCE OF COMPLEXES OF TITANIUM, ZIRKONIUM OR HAFNIUM RHONE-POULENC CHIMIE (FR) 1996-06-26 EP disclosed
WO-1995007312-A1 METHOD FOR THE PREPARATION OF POLYORGANOSILOXANES WITH INSATURATED FUNCTIONS BY DEHYDROGENOCONDENSATION IN THE PRESENCE OF COMPLEXES OF METALS OF GROUP IV RHONE-POULENC CHIMIE (FR) 1995-03-16 WO disclosed