SCHEMBL8668488

SCHEMBL8668488

CC(C)S(=O)(=O)N(C)c1[c]cccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1043536 0.79 KMT2A (0.38) TSHRPOLB
SCHEMBL8665905 0.78 ALOX5AP (0.34) TSHR
SCHEMBL5387281 0.78 KIF11 (0.34)
SCHEMBL6599939 0.78 TSHR (0.36) TSHR
SCHEMBL2536094 0.76 KCNE1 (0.33)
SCHEMBL5389269 0.75 TSHR (0.31) TSHRPOLB
SCHEMBL1043411 0.75
SCHEMBL10661809 0.74 KDM4E (0.30) POLB
SCHEMBL2200866 0.72
SCHEMBL12251459 0.71 CA12 (0.48) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750552-A ANTIULCER AGENTS ARAX CO., LTD. (JP) 1998-05-12 US disclosed
EP-0736527-A1 Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer ARAX CO., LTD. (JP) 1996-10-09 EP disclosed