Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 1/20 | 0.62 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.56 |
| ▸ | TTR | P02766 | 3/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.45 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589157 | 0.86 | CYP4F2 (0.53) | UNGFOLH1TTRCYP2C9MEP1B | |
| SCHEMBL5070742 | 0.82 | FOLH1 (0.63) | UNGFOLH1CYP2D6CYP2C9HIF1A | |
| SCHEMBL8367820 | 0.81 | LOXL2 (0.60) | FOLH1HIF1AP4HBKMT2A | |
| SCHEMBL22227442 | 0.80 | FOLH1 (0.61) | FOLH1CYP2D6CYP2C9HIF1AANPEP | |
| SCHEMBL7521628 | 0.80 | UNG (0.69) | UNGFOLH1TTRFBP1CYP2C9 | |
| SCHEMBL8717218 | 0.80 | PARP1 (0.47) | UNGFOLH1MEP1B | |
| SCHEMBL715984 | 0.79 | FOLH1 (0.59) | UNGFOLH1CYP2D6CYP2C9HIF1A | |
| Benzene SCHEMBL28254095 | 0.79 | FOLH1 (0.59) | UNGFOLH1CYP2D6CYP2C9HIF1A | |
| SCHEMBL13821237 | 0.78 | UNG (0.71) | UNGFOLH1TTRCYP2D6CYP2C9 | |
| 3-Formylbenzoic Acid SCHEMBL266698 | 0.77 | UNG (1.00) | UNGTTRFBP1CYP2C9P4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811422-A | USEFUL FOR TREATING VIRAL INFECTIONS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | disclosed |