Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 14/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666037 | 0.89 | HIF1A (0.36) | LMNAMAPK1HTTL3MBTL1HIF1A | |
| SCHEMBL8665232 | 0.89 | SMN1; SMN2 (0.39) | LMNAMAPK1HTTL3MBTL1HIF1A | |
| SCHEMBL8664803 | 0.81 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL9056021 | 0.77 | HIF1A (0.38) | HIF1A | |
| SCHEMBL9056852 | 0.68 | HIF1A (0.37) | HIF1A | |
| SCHEMBL9056334 | 0.68 | HIF1A (0.37) | HTTHIF1AMAPTSMN1; SMN2HPGD | |
| SCHEMBL5441258 | 0.67 | ALDH1A1 (0.53) | LMNAMAPK1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL28379077 | 0.67 | KMT2A (0.44) | LMNAL3MBTL1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5441256 | 0.67 | ALDH1A1 (0.53) | LMNAMAPK1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL28943651 | 0.65 | SMN1; SMN2 (0.45) | LMNAMAPK1L3MBTL1HIF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786374-A | FUNGICIDES, MICROBIOCIDES | NOVARTIS CORPORATION (US) | 1998-07-28 | — | — | US | claimed |