Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666037 | 0.93 | HIF1A (0.36) | SMN1; SMN2KMT2ARAB9AL3MBTL1ELANE | |
| SCHEMBL8668620 | 0.89 | LMNA (0.40) | SMN1; SMN2L3MBTL1HIF1AMAPTLMNA | |
| SCHEMBL8664803 | 0.80 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL9056852 | 0.79 | HIF1A (0.37) | HIF1AMTNR1AMTNR1B | |
| SCHEMBL9056334 | 0.72 | HIF1A (0.37) | SMN1; SMN2RAB9AHIF1AMAPTKDM4E | |
| SCHEMBL8664804 | 0.68 | ALDH1A1 (0.54) | SMN1; SMN2KMT2ARAB9AHIF1AMEN1 | |
| SCHEMBL9056021 | 0.67 | HIF1A (0.38) | HIF1A | |
| SCHEMBL28379077 | 0.63 | KMT2A (0.44) | SMN1; SMN2KMT2AL3MBTL1MEN1MAPT | |
| SCHEMBL5441258 | 0.63 | ALDH1A1 (0.53) | SMN1; SMN2KMT2ARAB9AL3MBTL1MEN1 | |
| SCHEMBL5441256 | 0.63 | ALDH1A1 (0.53) | SMN1; SMN2KMT2ARAB9AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786374-A | FUNGICIDES, MICROBIOCIDES | NOVARTIS CORPORATION (US) | 1998-07-28 | — | — | US | claimed |
| US-5786374-A | FUNGICIDES, MICROBIOCIDES | NOVARTIS CORPORATION (US) | 1998-07-28 | — | — | US | disclosed |