Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | IL1RN | P18510 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4827684 | 0.83 | SLC18A3 (0.40) | RXFP1SLC18A3CA1CA2CA9 | |
| SCHEMBL8670333 | 0.78 | NPC1 (0.47) | SLC18A3ALDH1A1NPC1RAB9AADRA2A | |
| SCHEMBL8670702 | 0.75 | NPC1 (0.40) | RXFP1CYP1A2SLC18A3CA1CA2 | |
| SCHEMBL6674584 | 0.74 | RXFP1 (0.51) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL30567319 | 0.74 | RXFP1 (0.51) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL2952459 | 0.74 | RXFP1 (0.51) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL8668258 | 0.73 | MAPT (0.38) | ALDH1A1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL6785452 | 0.68 | RXFP1 (0.44) | RXFP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL7983593 | 0.67 | RXFP1 (0.43) | RXFP1CA1CA2CA9LMNA | |
| SCHEMBL6609264 | 0.66 | RXFP1 (0.49) | RXFP1CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721234-A | TREATING CONVULSIONS, ANXIETY, CEREBRAL HYPOXIA/ISCHEMIA, PARKINSON*S DISEASE | WARNER-LAMBERT COMPANY (US) | 1998-02-24 | — | — | US | disclosed |
| WO-1996017832-A1 | NOVEL GLUTAMATE RECEPTOR ANTAGONISTS: FUSED CYCLOALKYLQUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1996-06-13 | — | — | WO | disclosed |