SCHEMBL8668628

SCHEMBL8668628

C=C(C)C(=O)OC(F)(C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28383405 0.98 ALDH1A1 (0.37) ALDH1A1TSHRTHRB
SCHEMBL28688495 0.98 ALDH1A1 (0.37) ALDH1A1TSHRTHRB
SCHEMBL751394 0.96 ALDH1A1 (0.38) ALDH1A1TSHRTHRB
SCHEMBL8667191 0.96 ALDH1A1 (0.38) ALDH1A1TSHRTHRB
SCHEMBL2400720 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTHRB
SCHEMBL5086534 0.90 ALDH1A1 (0.37) ALDH1A1TSHRTHRB
SCHEMBL7532269 0.90 ALDH1A1 (0.37) ALDH1A1TSHRTHRB
SCHEMBL676250 0.90 ALDH1A1 (0.37) ALDH1A1TSHRTHRB
SCHEMBL28378224 0.90 ALDH1A1 (0.37) ALDH1A1TSHRTHRB
SCHEMBL2396171 0.90 ALDH1A1 (0.37) ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665252-B1 Two-pack aqueous coating composition KANSAI PAINT CO LTD (JP) 1998-12-16 EP disclosed
US-5519089-A ALKOXYSILANE CONTAINING ACRYLIC COPOLYMER AND POLYISOCYANATE KANSAI PAINT CO., LTD. (JP) 1996-05-21 US disclosed
EP-0665252-A2 Two-pack aqueous coating composition KANSAI PAINT CO., LTD. (JP) 1995-08-02 EP disclosed
US-4812337-A METALLIC PIGMENT BASE COAT, CLEAR TOP COAT KANSAI PAINT COMPANY, LIMITED (JP) 1989-03-14 US disclosed
US-4732941-A POLYMER ADDED AS STABILIZER KANSAI PAINT COMPANY, LIMITED (JP) 1988-03-22 US disclosed