Nitroethane

Nitroethane

SCHEMBL8668685

CC[N+](=O)[O-].CN(C)Cc1ccccc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.65
TSHR P16473 3/20 0.65
TAAR1 Q96RJ0 1/20 0.52
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
CRHBP P24387 2/20 0.47
CRHR2 Q13324 2/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
AOC3 Q16853 1/20 0.45
LMNA P02545 3/20 0.44
HRH3 Q9Y5N1 1/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
RIPK1 Q13546 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9255683 0.88 ALDH1A1 (0.71) ALDH1A1TSHRTAAR1CYP1A2CYP2D6
Nitric Acid SCHEMBL27389059 0.86 ALDH1A1 (0.68) ALDH1A1TSHRTAAR1CYP1A2CYP2D6
Nitric Acid SCHEMBL9255679 0.85 ALDH1A1 (0.65) ALDH1A1TSHRTAAR1CYP1A2CYP2D6
Propane SCHEMBL29199487 0.81 TSHR (0.90) ALDH1A1TSHRTAAR1AOC3LMNA
Propane SCHEMBL7131520 0.81 TSHR (0.90) ALDH1A1TSHRTAAR1AOC3LMNA
SCHEMBL24735547 0.81 TSHR (1.00) ALDH1A1TSHRTAAR1AOC3LMNA
SCHEMBL27766437 0.81 TSHR (1.00) ALDH1A1TSHRTAAR1AOC3LMNA
SCHEMBL15900 0.81 TSHR (1.00) ALDH1A1TSHRTAAR1AOC3LMNA
SCHEMBL5014268 0.81 TSHR (1.00) ALDH1A1TSHRTAAR1AOC3LMNA
Formaldehyde SCHEMBL2648136 0.79 TSHR (0.85) ALDH1A1TSHRTAAR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750802-A (1R*, 2S)-1-phenyl-2-nitroalcohols and method for producing same AMVAC CHEMICAL CORPORATION (US) 1998-05-12 US disclosed