SCHEMBL8668775

SCHEMBL8668775

CCCCCCC(OC1CCCCO1)c1ccc(-c2ncc(O)cn2)cc1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
RARB P10826 1/20 0.33
RAB9A P51151 4/20 0.32
KDM4E B2RXH2 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
HSD17B10 Q99714 2/20 0.32
MAPT P10636 2/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
NPC1 O15118 3/20 0.31
GCGR P47871 1/20 0.30
SPHK2 Q9NRA0 2/20 0.30
SPHK1 Q9NYA1 1/20 0.30
KDM4C Q9H3R0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8671571 0.85 MEN1 (0.31) MEN1KMT2A
SCHEMBL9424628 0.79 MEN1 (0.33) MEN1KMT2ARAB9AKDM4ESMN1; SMN2
SCHEMBL8564925 0.78 RAB9A (0.37) MEN1KMT2ARARBRAB9AKDM4E
SCHEMBL8564929 0.78 MEN1 (0.33) MEN1KMT2ASPHK2KDM4C
SCHEMBL8566485 0.76
SCHEMBL9345719 0.71 RARB (0.41) MEN1KMT2ARARBRAB9AKDM4E
SCHEMBL9345707 0.71 RARB (0.41) MEN1KMT2ARARBRAB9AKDM4E
SCHEMBL9424549 0.71 PLA2G2A (0.40) MEN1KMT2ARAB9AKDM4ESMN1; SMN2
SCHEMBL8670843 0.70 KDM4E (0.40) MEN1KMT2ARARBRAB9AKDM4E
SCHEMBL7785424 0.70 MEN1 (0.36) MEN1KMT2ARARBRAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0667384-B1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL CO (JP) 1998-12-16 EP disclosed
EP-0667384-A1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-08-16 EP disclosed